Articles Tagged With:
Indications for Reduced-Dose Direct Oral Anticoagulants
A subgroup analysis of the ENGAGE-AF TIMI 48 study of edoxaban 60 mg/day vs. 30 mg/day compared to warfarin in patients with atrial fibrillation of the group 80 years of age or older has shown that 30 mg/day results in less major bleeding without a concomitant increase in stroke risk compared to 60 mg/day or warfarin.
Anchoring Alzheimer’s Disease Along an Amyloid Timeline
In 601 individuals from Wisconsin-based cohorts with amyloid-beta and tau positron emission tomography scans, the magnitude and topographical spread of tau pathology increased with longer duration of amyloid-beta positivity, and the cognitive decline was steepest in those with the longest duration of amyloid-beta positivity and elevated entorhinal tau.
Sweating for Sleep: Examining Evening Exercise and its Effects on Sleep Duration
This small, randomized crossover trial demonstrates that short, repetitive bouts of early evening exercise lead to an increase in total sleep time compared to prolonged sitting.
Multicomponent Breastfeeding Interventions in Women with a Body Mass Index > 25
The study found no statistically significant differences in breastfeeding outcomes between the intervention and control groups at various postpartum time points, although the intervention group received more hospital-based support, while the control group sought more private lactation support.
What Do Patients Know About Anti-Müllerian Hormone Testing?
In this randomized, controlled, online questionnaire trial, participants who received evidence-based information about anti-Müllerian hormone (AMH) testing had lower interest in getting an AMH test (mean difference, 1.05; 95% confidence interval, 0.83-1.30) than individuals who viewed the control information from a direct-to-consumer website.
Rethinking Endometrial Thickness Thresholds that Prompt Endometrial Biopsy to Rule Out Endometrial Cancer
In a retrospective review of 1,494 pre- and postmenopausal Black individuals who underwent transvaginal ultrasonography, 24 of 210 individuals (11.4%) with endometrial cancer had an endometrial thickness lower than the threshold for undergoing biopsy to detect cancer.
Reproductive Healthcare in Adolescents with Autism and Other Developmental Disabilities
This cohort study of 3,723 female adolescents from the Kaiser Permanente healthcare system in California found that adolescents with autism or developmental disability were less likely to see an OB/GYN or be prescribed contraception compared with their typically developing peers. This study identified disparities present in reproductive healthcare for this population, despite higher rates of menstrual-related diagnoses.
Emergencies in the First Week of Life
The first week of life is a critical period for newborns, marked by rapid physiological transitions and a heightened vulnerability to various medical emergencies. This article provides an in-depth exploration of several significant neonatal emergencies that can arise during this time.
Metabolic Dysfunction-Associated Steatotic Liver Disease
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic metabolic disease that you may never have heard of. MASLD, formerly known as non-alcoholic fatty liver disease (NAFLD), is the most prevalent liver disease worldwide. MASLD affects 30% of the world’s population, more than half of those people with obesity, and more than 70% of people with type 2 diabetes. While many clinicians may see patients with slightly elevated transaminases and assume it is fatty liver, MASLD is not benign and often begins well before laboratory changes. This article reviews the pathogenesis, diagnosis, and natural history of MASLD; known treatments; and future therapies.
Structural Racism Affects Family Planning and Needs Combatting, Study Says
Family planning has been linked with racism for centuries, and this legacy impact on 21st-century patients needs to be addressed in family planning research, a new paper says.